This self-assessment program consists of 3 modules engaging the reader to increase awareness of the role of macrophages in cardiovascular inflammation and atherothrombotic factors, to describe IL-6, CRP, and LDL-C as biomarkers of residual risk in contemporary practice, to increase awareness of the relationship between lipoproteins, thrombosis, and atrial fibrillation, as well as to analyze the combination of ezetimibe and moderate-intensity statin for patients with atherosclerotic cardiovascular disease and to describe the use of PCSK9, including inclisiran, to tackle cardiovascular risk.